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Overall, across the two repeat experiments for Cagri and CagriBB bound to the CTR, the conformational equilibrium between the bypass vs CT-like state was similar, suggesting that the salt bridge/ionic lock is sufficient to preferentially stabilize the bypass conformation at CTR (Supplementary Fig

Copper ionophores combined with radiotherapy have been found to reprogram CAR-T cells, thus overcoming stromal barriers in breast cancer models

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