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When MUT activity is impaired due to genetic mutations or functional vitamin B12 deficiency, methylmalonyl-CoA cannot be efficiently converted into succinyl-CoA

Effects on maternal bone were observed in pregnant and lactating rats in a pre- and postnatal toxicity study when esomeprazole magnesium was administered at oral doses of 14 to 280 mg/kg/day (about 3.4 to 68 times an oral human dose of 40 mg on a body surface area basis)

Exacerbation of symptoms of myasthenia gravis and new onset of myasthenic syndrome have been reported in patients receiving azithromycin therapy

Joint health: Intra-articular AOD-9604 enhanced cartilage regeneration in rabbit OA models, with combined AOD-9604 + hyaluronic acid outperforming either alone (Kwon & Park, 2015)