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The underlying pathologic mechanisms of primary MS fatigue are poorly understood, with proposed theories including structural damage of white and gray matter, inflammatory processes including elevated cytokines, endocrine dysfunction, and maladaptive network recruitment attributable to distributed lesions or inflammation

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5-Amino-1MQ is a small-molecule research compound studied for its role in metabolic regulation and fat metabolism pathways

doi: 10.1016/j.chom.2015.04.007 [DOI] [PMC free article] [PubMed] [Google Scholar] 15

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