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Research in diet-induced obese animal models reveals tesofensine reduces body weight more effectively in obese subjects compared to lean subjects, suggesting enhanced efficacy in the metabolic conditions for which it is intended

Thinning or fragile skin

Intercurrent events such as smoking cessation, switching to or adding another weight-loss treatment, or treatment discontinuation, can be unbalanced between treatment arms and impact the endpoint of interest, and subsequent data analysis and interpretation

Do not use in combination with tetracyclines

Several commonly used herbal supplements can interact with blood pressure medications