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In an MPTP-induced Parkinson's disease animal model, intracerebroventricular injection of PBzyme decreases dopaminergic degradation and inhibits neuroinflammation by downregulating the activation of microglial nucleotide-binding domain and leucine-rich repeat family pyrin domain containing 3 (NLRP3) inflammasomes and caspase-1 by scavenging reactive oxygen species which ultimately leads to microglia pyroptosis (Ma et al., 2022)

J Ethnobiol Tradit Med 118:228237 Petronelli A, Pannitteri G, Testa U (2009) Triterpenoids as new promising anticancer drugs

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On dermoscopy, after 3 months of treatment, some improvement was noted on right side in the form of decreased shades of pigmentary network in cases of epidermal melasma and decreased irregularity of pigmentary network, decreased number of granules and globules in cases of mixed melasma in comparison with baseline

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