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Concomitantly, a phase I clinical trial using NSCs derived from fetal cortices, genetically engineered to overexpressed the trophic factor glial cell line-derived neurotrophic factor (GDNF) [155], will be conducted through Californias stem cell agency ( The transplantation of SOD1 G93A fALS rats using a similar approach protected the integrity of motor neuron cell bodies, but failed to preserve neuromuscular junctions or increase the life-span of the animals [155]

doi: 10.1016/j.tim.2023.03.018 53

They are medium-sized muscles, located deep in the buttock, beneath the Gluteus maximus muscle.(fig.1) They start mostly at the sacrum (lower spine) and connect to tip of each femur (thigh bone), running approximately horizontally