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Description

When a full blood count reveals macrocytosis (enlarged red blood cells, indicated by a raised MCV), this should prompt investigation for B12 or folate deficiency before relying on HbA1c for diabetes management decisions

UK adults aged 1964 years should take 1.5 micrograms of vitamin B12 daily, whilst breastfeeding mothers require 2.0 micrograms

Clinical trials conducted in the early 2000s showed modest results, and the compound failed to demonstrate sufficient efficacy to support regulatory approval as a weight-loss medicine