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ROS active many signaling kinases (e.g., mitogen activated protein kinases), transcription factors (e.g., nuclear factor kB [NF-kB] and nuclear factor of activated T-cells [NFAT]), molecules that participate in calcium mobilization (e.g., ryanodine receptors [RyR2], SERCA 2A, calcium/calmodulin-dependent protein kinase II [CaMKII]), antioxidant proteins and others molecules involved in cardiac hypertrophy [151,152]

It is produced by the body, recycled continuously and is found in fairly high concentrations in most human cells

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BPC-157 (Body Protection Compound-157) is a synthetic 15-amino-acid peptide derived from a protective protein found naturally in human gastric juice