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72 Chronic metformin treatment first became known as a pharmacological cause of vitamin B 12 deficiency within a decade of it coming into use and more recently decreased serum folate concentration has also been associated with its administration

Rather than megadosing B12, it includes it as part of a tightly formulated multivitamin alongside omega-3, vitamin D, magnesium and various other cognitive-supporting nutrients

MV has served as an advisory board member and/or consultant and has received fees/speakers honoraria and/or has participated in clinical trials for AbbVie, Almirall, Amgen, Bristol Myers Squibb, Boehringer-Ingelheim, Eli Lilly, Galderma, Janssen, Leo Pharma, Novartis, Pierre Fabre, and UCB Pharma