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The number of patients needing dialysis in China is rising rapidly, with 207,863 new cases in 2023, increasing the total number to 1 million (Webster et al., 2017)

Potential roles in destructive lung disease

Semenza GL (2012) Hypoxia-inducible factors in physiology and medicine

Conserv Physiol 3:cov024 Costantini D, DellOmo G, De Filippis PS, Marquez C, Snell H, Snell H, Tapia W, Brambilla G, Gentile G (2009) Temporal and spatial covariation of gender and oxidative stress in the Galpagos land iguana Conolophus subcristatus

they are the subject of intense interest across drug discovery, regenerative medicine, anti-aging, obesity, and metabolic research, but they are also delicate, hygroscopic, and easily denatured