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The brain metastasis in breast tumor can result from HER2 upregulation and ER downregulation

BDNF, p-CREB, p65 NF-B, PSD-95, and Synaptophysin Assay Using Western Blot Samples from different groups were loaded on SDS-PAGE gel with 4 g proteins content then transferred to polyvinylidene fluoride (PVDF) membrane and blocked in 5% non-fat dry milk in Tris-buffered saline, 0.1% Tween 20 (TBST)

It has hydrating properties that help balance the skins moisture levels and strengthen the skins natural barrier

They reduce mitochondrial oxidative damage by restricting mitochondrial ROS generation and increasing mitochondrial antioxidant systems such as mitochondrial SOD

Activation of this pathway has been suggested as a potential interventional approach to alleviating epilepsy and associated comorbidities [223]