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A drop in GSH or loss of GPX4 activity is usually enough to trigger ferroptosis (Eagle, 1955)

The reduction of CoQ10 to ubiquinol not only impedes the onset but also the propagation of lipid peroxidation processes in the membranes (157,158)

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These observations hint at the theory that the increase in both cortical and total BMC may potentially stem from improved bone growth leading to expanded bone dimensions, with the volumetric BMD staying consistent