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Low glutathione levels can lead to dangerous conditions and irritating symptoms, and low levels are also associated with worsening symptoms from serious diseases such as cystic fibrosis, AIDS, HIV, macular degeneration, Parkinsons disease, COPD, Alzheimers, other neurodegenerative disorders, and things as common as aging

The glutathione reductase enzyme turns oxidized GSSG back into active GSH

For this reason, it is crucial to be informed about one's own genetic variants of the MTHFR gene in order to focus on proper diet and monitor homocysteine levels in the blood