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Description

At the very least, immunogenicity would trigger the production of antibodies that neutralize the peptides effects

Cell Tissue Res

The synthetic mRNA construct of claim 1, wherein the mRNA construct comprises 5' cap m7GpppGm, a 5' UTR of A1G AT1G58420 (SEQ ID NO: 10), a Kozak sequence (SEQ ID NO: 121), a coding sequence encoding human coagulation factor IX (F9), one 3' UTR of human alpha globin (hAG) (SEQ ID NO: 81), and a poly(A) tail

To extend these results, we performed iWAT immunostainings with antibodies directed against multiple mitochondrial proteins

[00346] Examples of genes for which a translatable molecule can be used to express the corresponding peptide or protein include: Duchenne muscular DMD, BMD dystrophy, 310200 (3) AIDS, delayed/rapid KIR3DL1, NKAT3, NKB1, AMBl l, KIR3DS1 progression to (3)