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Mass spectrometry Whole-cell proteome (WCP) was performed in HeLa Flp in T-Rex TM RNF4 WT cells, pretreated with doxycycline (1 g/ml) for induction of RNF4 expression for 24 h before addition of PROTACs with a final concentration of 5 M

5-Amino-1MQ has the molecular formula C10H11N2 and a molecular weight of 159.21 g/mol

NMDA was used to induce acute injury in primary rat cortical neurons, which markedly increased HTT mRNA expression within a short time, as well as increased the expression of caspase-6 , caspase-3 , and caspase-8 [92]

Mechanisms 1 and 2 represent hydride gain, in which the molecule gains what amounts to be one hydride ion