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Renadyl is designed to act through the gut-kidney axis, where the probiotic strains metabolize uremic toxins in the colon, thereby facilitating their diffusion from the bloodstream and subsequent fecal elimination

Accessed 03/02/2023

Additionally, activated endothelial cells produce cytokines, chemokines, and adhesion molecules, amplifying the immune response [106,107,108,109]

In the present study, we review the role of several related E3 ubiquitin ligases and deubiquitinating enzymes (DUBs) on the pathogenesis of PD such as Parkin, CHIP, USP8, etc