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Gene set enrichment analysis (GSEA) was performed with 1000 permutations to identify enriched biological functions and activated pathways from the molecular signatures database (MSigDB), which included hallmark gene sets, positional gene sets, curated gene sets, motif gene sets, computational gene sets, GO gene sets, oncogenic gene sets, and immunologic gene sets

doi: 10.1089/jop.2011.0062 31 LeruezSMarillABressonTDe Saint MartinGBuissetAMullerJet al

As the original source of ATMs, this phenomenon also provides a certain basis for the possibility of ferroptosis of ATMs

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However, topical application with microneedling can significantly enhance absorption, approaching injectable effectiveness for some users