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In any case, we examined EAAC1 KO mice before 3 months old when no neurodegeneration was observed in the brain

suis for 24 hours in MEM significantly lowered the extracellular concentrations of serine (p 0.05, Table S2)

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We also noted pronounced enrichments for several genera that had MR pairs shared by pairs of the tissues, including Intestinibacter regulation shared by transverse and sigmoid colons, Ruminococcus gnavus, Lachnospiraceae UCG008 shared by sigmoid colon and ileum, and Olsenella and Desulfovibrio shared by ileum and transverse colon (Fig