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GWAS investigates potential therapeutic targets and predicts disease risk by examining the correlation of genes with genetic phenotypes 14

For instance, histone H1.3 exerts a suppressive effect on the expression of H19 and inhibits the proliferative capacity of ovarian cancer cells

Chest (1995) 107(4):106273

HK Lewis and Co Melov S, Schneider JA, Day BJ, Hinerfeld D, Coskun P, Mirra SS, Crapo JD, Wallace DC (1998) A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase