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This is accompanied by loss of the glycocalyx and a 60% increase in permeability of the vascular endothelium, a change that is even more pronounced in patients who die as a result of sepsis, indirectly demonstrating that sepsis leads to the degradation of the glycocalyx and a compensatory increase in glycocalyx synthesis by endothelial cells (60)

[DOI] [Google Scholar] 49.Alla V, Abraham J, Siddiqui J, Raina D, Wu GY, Chalasani NP, et al