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2007 Jan;35(1):75-83

This dual role of mtDNA, initiator of acute responses and perpetuator of chronic inflammation, links metabolic distress to progressive neuronal injury in aging and NDDs

In resource-limited environments for advanced Head And neck squamous cell carcinoma, the incorporation of low-dose nivolumab into triple metronomic chemotherapy enhanced 1-year Survival rates from 16.3 to 43.4% without a rise in severe toxicity, presenting a cost-effective option [100]