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While DSIP was primarily believed to be involved in sleep regulation due to its apparent ability to induce slow-wave sleep in rabbits, subsequent studies on the subject have been contradictory

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El-Fouly MZ, Sharaf AM, Shahin AAM et al (2015) Biosynthesis of pyocyanin pigment by Pseudomonas aeruginosa

86 Notch signaling pathway Notch signaling, intimately involved in embryonic development and maintenance of multicellular organisms in adults, is activated by ligand-receptor interaction between adjacent cells, which leads to successive proteolytic cleavages and releases the notch intracellular domain (NICD)

[32] Recently, the Kings CollegeCriteria were updated and the new guidelines have a high sensitivity and specificity when applied in our current intensive care unit (ICU) setting