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Neuroinflammation or fever is presumed to also trigger ISR, as autoantibodies may target neural or immune systems and cause inflammation elsewhere (418)

For example, foliar application of SA can stimulate SAR and effectively prevent the development of Fusarium wilt [166]

Bhat, M

Mechanistically, FSP1 functions at the membrane as an NAD(P)H-dependent CoQ 10 oxidoreductase, reducing CoQ 10 to its active form, CoQ 10 H 2 , which is a potent antioxidant for mitochondria and lipids (9799)

From refining biomarker strategies to uncovering therapeutic gaps, fit-for-purpose disease registries can help researchers build therapies that better reflect patient realities, not just lab models