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4.4 Robust radiotherapy Radiotherapy (RT) is critical for cancer therapy, and about 50% of patients will receive ionizing radiation during their treatment period (Moding et al., 2013)

M., Harpstrite, S

doi: 10.1007/s10096-016-2669-x 89 TanW.ChenR.SongJ.HeD.WuJ.ChenX.et al

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Using codon-randomizing mutagenesis to generate a clone library bearing nearly 80% of all possible amino acid changes, we measured the functional consequences of CBS variation by measuring the effects of selection on allele frequencies during a competitive yeast complementation assay using next-generation sequencing