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We're talking about a process that takes 40-50 years, maybe becoming a 38-year process

LPS induces inflammation through binding to the Toll-like receptors (TLRs) on Kupffer cells and encourages the release of pro-inflammatory cytokines, which are crucial factors in liver damage

Apr 17 2021;13(4)doi:10.3390/nu13041344 Alehagen U, Alexander J, Aaseth J, Larsson A, Lindahl TL

The timing remains similar to injection protocols (1-3 hours before activity) with possibly 30-45 minute faster onset due to direct mucosal absorption