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Additionally, unmodified PLGA nanoparticles are cleared rapidly by the spleen and liver through the reticuloendothelial system (RES), shortening their circulation time and therapeutic window 99

T-tests or Mann-Whitney U-test will be done to compare the continuous variables between the groups

The result of polypeptides is just the opposite, because polypeptides are generally obtained by enzyme hydrolysis

To induce mitochondrial mistranslation, we used the peptide mimetic actinonin (ACT) resulting in the accumulation of mistranslated, membrane-inserted mitochondrial proteins causing subsequent membrane potential loss 16,17,18,19,20,21

10.1080/14728214.2018.1527899 [DOI] [PubMed] [Google Scholar] 427.Hollister, A