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The FDA approved generic versions of Vyvanse from 11 drugmakers, including U.S.-based drugmakers Mallinckrodt and Viatris, UK-based Hikma Pharmaceuticals, and Indian drugmaker Sun Pharmaceutical Industries, last year after Takeda lost exclusivity over the drug

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Initially, studying desensitization was made possible by using experimental models endogenously expressing OR such as brain membranes, rabbit cerebellum or cell lines (NG 108-15, SH-SY5Y, SK-N-SH, SK-N-BE)

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