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Complementary mechanisms GSH and TXN systems constitute the two thiol-based antioxidant networks that cooperate to restrain ferroptosis 115

5.5 Lactate accumulation: acidification and inhibition of antitumor immunity In the complex, dynamic tumor microenvironment of colorectal cancer, metabolic reprogramming of cancer cellsparticularly the enhanced Warburg effectserves not only as a core strategy to meet bioenergetic and biosynthetic demands but also as a key driver of immunosuppression

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Studies of this phenomenon have been hampered by the challenge of identifying patient populations that consistently have low glutathione levels

Magnesium silicate sprays (MSSs) exhibit improved degradability and excellent bioactivity for the promotion of cell proliferation and migration