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10.1016/j.aanat.2018.11.005 110 KanaiM.YoshimuraK.AsadaM.ImaizumiA.SuzukiC.MatsumotoS.et al (2011)

Zhang RX, Kang R, Tang DL

Curr Biol 8(24):R883R885 Wu YJ, Krttgen A, Mller JC, Shine D, Chan JR, Shooter EM, Cosgaya JM (2004) Nerve growth factor, brain-derived neurotrophic factor, and neurotrophin-3 are sorted to dense-core vesicles and released via the regulated pathway in primary rat cortical neurons

and (4) basket trials as helpful adjuncts to traditional clinical trial design

In contrast to findings in the APPROACH and COMPASS trials, volanesorsen or olezarsen ASO treatment did not significantly alter plasma LDL-cholesterol concentration in patients with mild-to-moderate HTG [81, 88]