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On the other hand, among the 33 hub genes identified as potentially important in the hsa04010: MAPK signaling pathway of NP against SCA3, we identified CACNA1B, TNF, CACNA1H, RELA, EGFR, IKBKB, RPS6KA3, IRAK1, ERBB2, RPS6KA1, AKT1, MAPK1, IKBKG, PRKACA, MAP4K4, PRKCG, MAP4K2, HSPA8, JUN, MAP2K2, DUSP3, CHUK, PRKCA, MAPK14, VEGFA, PPM1A, TAOK1, IL1B, MAPKAPK2, MAPT, TP53, MAP3K14, and HSPA1A (Table S12)

While these ROS serve antimicrobial functions, excessive generation may cause oxidative damage to host cells, precipitating OS ( The intestinal barrier integrity is damaged by enhanced OS

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coli NEBExpress was first transformed with the pKD46 plasmid and then typically grown in 2 L Terrific Broth (TB) medium supplemented with 100 g/mL Amp at 30 C in the presence of 0.2 % (w/v) arabinose to induce expression of the Red genes

Iron deficiency often shows up before anemia does, and oral supplements dont always work or absorb well