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YLL was supported by NIH grant T32AI138932, and KMM was supported by NIH grant T32CA009592

A key antioxidant produced in the body, important for neutralizing free radicals, supporting detoxification, and maintaining cellular health

doi: 10.3389/fendo.2025.1587891 Received 05 March 2025 Accepted 24 June 2025 Published 16 July 2025 Volume 16 - 2025 Edited by Lawrence Merle Nelson, Mary Elizabeth Conover Foundation, Inc., United States Reviewed by Roger Smith, The University of Newcastle, Australia Qinqin Gao, First Hospital of Soochow University, China Updates Copyright 2025 Anti, Gheorghe, Deming, Adeoye, Zhang and Mata-Greenwood

We need to learn how safe it is over a long time and understand the specific biological pathways that are involved

Most adults need 2.4 mcg per day, but vegetarians, vegans, masters athletes over 50, and high-volume endurance athletes are at elevated deficiency risk