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and Rumex abyssinicus with Allium sativum (Supplementary material 1)

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In the face of abiotic stresses such as drought and heavy metal exposure, plants utilize GSTs for detoxification and antioxidant defense, as these enzymes facilitate the conjugation of glutathione (GSH) with toxic compounds

Prodrugs are conjugated to RNA nanoparticles via efficient click chemistry, creating an ester linker that is cleaved by esterases in tumor tissues or cells, allowing the prodrugs to return back to their original structures and chemistry upon delivery and release, minimizing toxicity

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