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The B12 Deficiency Itself People fail to realize that when patients suffer from B12 deficiency, very often the disease is only diagnosed at its end stage

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J Food Sci Technol 57:927933

There are other alkylating agents used earlier for masking GSH in glutathione assay like N-ethyl-maleimide, 2-Vinylpyride etc

Even experienced doctors are sometimes stumped when interpreting high B12 blood values, so here is a little guide on how to proceed in such cases: Guide to High Vitamin B12 Blood Levels Sources E