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The primary theory is that SF elicits oxidative stress and cellular damage (Shamsuzzaman et al., 2003)

Hill DB, Long RF, Kissner WJ, et al

Recent animal experiments have shown that intracortical injection of the GABAA receptor agonist clonazepam and the GABAB receptor agonist baclofen into the medial prefrontal cortex of ASD model mice induced by VPA can effectively alleviate ASD-like behaviors

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NOX1 is expressed in epithelial cells in the colon, placenta, prostate, and uterus, as well as in vascular smooth muscle cells, astrocytes, microglia, neural cells, and retinal pericytes