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Current personalized radiogenomics approaches for all indications include a 10-gene signature for radiosensitivity, which includes expression scores for AR , JUN , STAT1 , PKCB , RELA , ABL1 , SUMO1 , PAK2 , HDAC1 , and IRF1 [31]

Figure 2 It is worth noting that appropriate surface modifications can alter a drugs organ-targeting profile, enabling more precise delivery and allowing repurposing of existing materials, which helps reduce costs

Meanwhile, selenium-containing antioxidant enzymes in myocardial tissue are involved in the removal of H 2 O 2 in myocardial cells, thereby protecting the proper function of cellular organelles such as the myocardial cell membrane and mitochondria

Medically reviewed by Alan Lucks | MD , Alan Lucks MDPC Private Practice - New York on June 22nd, 2023

Human MutT homolog protein 1 (hMTH1), which catalyzes the hydrolysis of oxidized purine nucleoside triphosphates, is also a biomarker of oxidative DNA damage [34]