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We hypothesized that exposure to air pollution during the prenatal period was associated with prolonged changes in mitochondrial respiration, a key physiological system known to be disrupted in children with ASD and influenced by environmental factors

doi: 10.1056/NEJM199602293340906 81 BhilareNVShedgeRTambePMMoreA

However, this doesnt explain: Why some antidepressants cause much more weight gain than others (if it were just depression lifting, all antidepressants would cause similar weight gain) Why weight gain continues long after depression has stabilized Why patients on bupropion dont gain weight despite depression improvement The eating more because depression lifted explanation is often used to dismiss medication effects, but the evidence clearly shows medication-specific effects beyond depression improvement