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After initial repletion, a maintenance dose is given, often 1,000 mcg intramuscularly every month or every 2 to 3 months, to prevent recurrence of deficiency

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This essential water-soluble vitamin plays a role in many bodily functions, including the production of DNA, red blood cells, and nerve cells

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Heffernan, Jiang, Thorburn, and Ng reported in the American Journal of Physiology that oral administration of AOD9401 to ob/ob mice was associated with reduced body-weight gain, altered adipose lipogenic and lipolytic activity, and acute changes in energy expenditure, evidence that a growth-hormone C-terminal fragment could act after oral delivery in a rodent model [3]