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In addition, COX-2 is the main trigger of oxidative and inflammatory responses that are often detected in photoaging and other stress/inflammatory disorders (138)

Lord C, Brugha TS, Charman T, Cusack J, Dumas G, Frazier T, et al

10.1128/IAI.00348-16 Infect

One of the uses of knowing the transcriptomes of a given animal species is that when an antibody study involves false negatives in which case the gene is expressed but not captured by the test (119)