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Several therapeutic targets have been identified, including osteopontin, cysteinyl leukotriene 2 receptor, the opioid receptor antagonist -funaltrexamine, and PPAR and RXR agonists

Specifically, researchers are investigating the mitochondriathe microscopic powerhouses within our cells responsible for generating the energy required for every bodily function

Tissues collected post-mortem atday2 post Co-60 exposure were found to contain measurable amounts of radioactivity with the highest levels in the liver (FIG

PPAR antagonists can block the increase of PPAR DNA binding activity and antioxidant enzymatic activities (SOD), inhibiting the protection of PPAR activation in OGD-exposed neurons 137

Robust human mechanism data are not yet available