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doi: 10.1038/s41467-019-11911-5 174 KhanANMNHEmmonsTRMagnerWJAlqassimESingelKLRicciutiJet al

Furthermore, ROS play a multitude of additional roles in initiating the T cell response, such as activating key transcription factors (e.g., NF-B, AP-1) and the mechanistic target of rapamycin complex 1 (mTORC1), the master regulator of cellular metabolism (79)