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OH radicals initiate the lipid peroxidation process of cellular membranes, which in turn may result in the release of iron into the cytosol and contribute to the formation of a labile iron pool (Kurz et al., 2011[257])

The LDL cholesterol is taken into cells via cholesterol receptors, where it is transferred into the mitochondria to be converted into pregnenolone

Since L-citrulline can be readily converted to L-arginine, it provides a recycling pathway for the conversion of L-citrulline to NO via L-arginine [14, 17]

& Harwood, C

Silencing GSK3 in immortalized wild-type hepatocytes (Supplementary Figure 5) prolonged Nrf2 nuclear accumulation up to 24 h upon APAP treatment as observed in PTP1B / cells (Figures 4b and 5a)