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Rojewski MT, Baldus C, Knauf W, Thiel E, Schrezenmeier H (2002) Dual effects of arsenic trioxide (As2O3) on non-acute promyelocytic leukemia myeloid cell lines: induction of apoptosis and inhibition of proliferation

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48 Besides adenovirus, vesicular stomatitis virus can also be modified and used to produce the COVID-19 vaccine, inducing a stronger humoral immune response via intranasal and intramuscular routes

However, the need to measure biomarker modulation in tumor tissue, an invasive procedure for patients with solid tumors, severely limits sampling frequency and consequently hinders the establishment of a PK/PD model in humans