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Human evidence note: While practitioner reports and early clinical experience are accumulating, large, controlled human trials are still limited

Identification of biomarkers of immune checkpoint blockade efficacy in recurrent or refractory solid tumor malignancies

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W modelach in vivo (mysz SHR, szczur) analizuje si parametry przeywalnoci, markery stresu oksydacyjnego, profil wydzielania melatoniny i funkcj osi neuroendokrynnej w dugoterminowych protokoach ekspozycji