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2.2.2 Accelerated senescence model (SAMP, H 2 FPEF score 2) The senescence accelerated prone (SAMP) strain was generated by selective inbreeding of AKR/J mice (Takeda et al., 1997)

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Furthermore, antiviral assays revealed that 0.4 mg/mL of almond polyphenols reduced both the expression of viral proteins and the accumulation of viral DNA (349)

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Given the heterogeneity of NPCs, we further analyzed the scRNA-seq data (GSE165722) 26 from human NP tissues with mild (grades II and III) and severe (grades IV and V) degeneration to identify the potential pathogenic factors associated with IDD