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71 Therapeutic modulation of the autophagy-mitophagy axis in metabolic diseases Pharmacological interventions Several pharmacological agents already in clinical use exert metabolic benefits, at least in part, through activation of autophagy and mitophagy

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doi: 10.3389/fphar.2026.1674533 Received 03 August 2025 Revised 04 February 2026 Accepted 06 February 2026 Published 11 March 2026 Volume 17 - 2026 Edited by Micha Tomczyk, Medical University of Bialystok, Poland Reviewed by Sidharth Prasad Mishra, University of South Florida, United States Qiao Zhang, Shaanxi University of Chinese Medicine, China Updates Copyright 2026 Peng, Jiang, Tan and Jiang

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17% and 8% of the men decreased or increased their dose, respectively