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Ferroptosis: whERe is the critical site of lipid peroxidation

Interestingly, a role for UCP2 in the transport of mitochondrial glutathione has been reported in neurons (de Bilbao et al., Mitochondria contain a myriad of antioxidant defense enzymes and low molecular weight molecules that degrade both O 2 and H 2 O 2 with exquisite efficiency (Mailloux et al., 2013a)