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Purity issues, even small ones, can throw off an entire study, so researchers tend to be picky about sourcing for good reason

however, when high amounts of Mn are added to the drinking water, Slc39a14 Vil1/Vil1 mice exhibit significant systemic Mn accumulation and exacerbated brain Mn overload, which are associated with clear early signs of manganism, including motor coordination deficits and dysautonomia 53