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SUSTAIN 9: Ozempic injection as an add-on to SGLT-2i MET/SU 6 Study design: 30-week, multinational, randomized, double-blind, parallel-group, placebo-controlled trial evaluating the efficacy and safety of adding Ozempic injection 1 mg to SGLT-2i metformin/sulfonylurea vs SGLT-2i + placebo metformin/sulfonylurea

Ozempic Common Side Effects Nausea, vomiting, diarrhea, stomach (abdominal) pain, and constipation [8] Serious Side Effects Thyroid tumor/cancer, pancreatitis, gallbladder problems, low blood sugar, kidney problems, changes in vision, or allergic reactions [8] Reybelsus Common Side Effects Nausea, stomach (abdominal) pain, diarrhea, decreased appetite, vomiting, and constipation [9] Serious Side Effects Thyroid tumor/cancer, pancreatitis, gallbladder problems, low blood sugar, kidney problems, changes in vision, or allergic reactions [9] Wegovy Common Side Effects Nausea, diarrhea, vomiting, constipation, stomach (abdominal) pain, headache, tiredness (fatigue), upset stomach, dizziness, feeling bloated, belching, low blood sugar in people with type 2 diabetes, gas, stomach flu, heartburn, and runny nose or sore throat [10] Serious Side Effects Thyroid tumor/cancer, pancreatitis, gallbladder problems, low blood sugar, kidney problems, changes in vision, allergic reactions, increased heart rate, depression, or thoughts of suicide [10] How much does Ozempic cost

GLP1 receptor activation can reduce appetite, slow stomach emptying, and improve glucose control by increasing insulin release when glucose is high and reducing glucagon when appropriate