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The research group belongs to the validated Research Groups Ref

Mouse models demonstrate that ethanol upregulates HDAC2/3 in the NAc and PFC, repressing genes involved in synaptic plasticity (e.g., Arc , Bdnf )

Activated T cells express integrins and chemokine receptors that allow them to adhere to and penetrate the brain endothelial lining, which is often upregulated with adhesion molecules during MS flares

In vivo , findings demonstrate that the overexpression of indoleamine 2,3-dioxygenase (IDO) restricts ATP production in CD8+ cells, whilst in vitro studies indicate this effect is mediated by reduced activity of electron transport chain complex I, which accounts for the decreased ATP production observed in infiltrating T cells (Liu et al., 2009)

They work in the same way: they reduce the repeated facial motions and expressions that create wrinkles