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Some genes such as ITGAM and FCR can potentially affect the recruitment of myeloid cells to the glomerular matrix by binding to the immune complexes in the glomerulus (103)

Approximately 85.8% of deaths related to iNTSs occur in sub-Saharan Africa, where HIV, immunodeficiency disorders (e.g., chronic granulomatous disease), malnutrition, and recent malaria or sickle cell anemia increase the risk of infection by iNTSs (Stanaway et al., 2019